Pesquisa | Secretaria de Estado da Saúde

1.

The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression.

Wang, Qiankun; Clark, Kolin M; Tiwari, Ritudhwaj; Raju, Nagarajan; Tharp, Gregory K; Rogers, Jeffrey; Harris, R Alan; Raveendran, Muthuswamy; Bosinger, Steven E; Burdo, Tricia H; Silvestri, Guido; Shan, Liang.

Cell ; 187(5): 1223-1237.e16, 2024 Feb 29.

Artigo Inglês | MEDLINE | ID: mdl-38428396

2.

Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model.

Chen, Yefei; Hong, Zexuan; Wang, Jingyi; Liu, Kunlin; Liu, Jing; Lin, Jianbang; Feng, Shijing; Zhang, Tianhui; Shan, Liang; Liu, Taian; Guo, Pinyue; Lin, Yunping; Li, Tian; Chen, Qian; Jiang, Xiaodan; Li, Anan; Li, Xiang; Li, Yuantao; Wilde, Jonathan J; Bao, Jin; Dai, Ji; Lu, Zhonghua.

Cell ; 186(24): 5394-5410.e18, 2023 11 22.

Artigo Inglês | MEDLINE | ID: mdl-37922901

3.

Publisher Correction: Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues.

Cella, Marina; Gamini, Ramya; Sécca, Cristiane; Collins, Patrick L; Zhao, Shanrong; Peng, Vincent; Robinette, Michelle L; Schettini, Jorge; Zaitsev, Konstantin; Gordon, William; Bando, Jennifer K; Yomogida, Kentaro; Cortez, Victor; Fronick, Catrina; Fulton, Robert; Lin, Lih-Ling; Gilfillan, Susan; Flavell, Richard A; Shan, Liang; Artyomov, Maxim N; Bowman, Michael; Oltz, Eugene M; Jelinsky, Scott A; Colonna, Marco.

Nat Immunol ; 20(10): 1405, 2019 Oct.

Artigo Inglês | MEDLINE | ID: mdl-31388149

4.

Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues.

Cella, Marina; Gamini, Ramya; Sécca, Cristiane; Collins, Patrick L; Zhao, Shanrong; Peng, Vincent; Robinette, Michelle L; Schettini, Jorge; Zaitsev, Konstantin; Gordon, William; Bando, Jennifer K; Yomogida, Kentaro; Cortez, Victor; Fronick, Catrina; Fulton, Robert; Lin, Lih-Ling; Gilfillan, Susan; Flavell, Richard A; Shan, Liang; Artyomov, Maxim N; Bowman, Michael; Oltz, Eugene M; Jelinsky, Scott A; Colonna, Marco.

Nat Immunol ; 20(8): 980-991, 2019 08.

Artigo Inglês | MEDLINE | ID: mdl-31209406

5.

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.

Ho, Ya-Chi; Shan, Liang; Hosmane, Nina N; Wang, Jeffrey; Laskey, Sarah B; Rosenbloom, Daniel I S; Lai, Jun; Blankson, Joel N; Siliciano, Janet D; Siliciano, Robert F.

Cell ; 155(3): 540-51, 2013 Oct 24.

Artigo Inglês | MEDLINE | ID: mdl-24243014

6.

Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4⁺ T Cells Permissive for Latent HIV-1 Infection.

Shan, Liang; Deng, Kai; Gao, Hongbo; Xing, Sifei; Capoferri, Adam A; Durand, Christine M; Rabi, S Alireza; Laird, Gregory M; Kim, Michelle; Hosmane, Nina N; Yang, Hung-Chih; Zhang, Hao; Margolick, Joseph B; Li, Linghua; Cai, Weiping; Ke, Ruian; Flavell, Richard A; Siliciano, Janet D; Siliciano, Robert F.

Immunity ; 47(4): 766-775.e3, 2017 10 17.

Artigo Inglês | MEDLINE | ID: mdl-29045905

7.

Chemical inhibition of DPP9 sensitizes the CARD8 inflammasome in HIV-1-infected cells.

Clark, Kolin M; Kim, Josh G; Wang, Qiankun; Gao, Hongbo; Presti, Rachel M; Shan, Liang.

Nat Chem Biol ; 19(4): 431-439, 2023 04.

Artigo Inglês | MEDLINE | ID: mdl-36357533

8.

Human neutrophil development and functionality are enabled in a humanized mouse model.

Zheng, Yunjiang; Sefik, Esen; Astle, John; Karatepe, Kutay; Öz, Hasan H; Solis, Angel G; Jackson, Ruaidhrí; Luo, Hongbo R; Bruscia, Emanuela M; Halene, Stephanie; Shan, Liang; Flavell, Richard A.

Proc Natl Acad Sci U S A ; 119(43): e2121077119, 2022 10 25.

Artigo Inglês | MEDLINE | ID: mdl-36269862

9.

Design and synthesis 1H-Pyrrolo[2,3-b]pyridine derivatives as FLT3 inhibitors for the treatment of Acute myeloid Leukemia.

Wei, Tian-Hua; Zhou, Yun; Yang, Jin; Zhang, Meng-Yuan; Wang, Jing-Jing; Tong, Zhen-Jiang; Wu, Jia-Zhen; Wang, Yi-Bo; Sha, Jiu-Kai; Chen, Min; Ding, Ning; Yu, Yan-Cheng; Dai, Wei-Chen; Leng, Xue-Jiao; Xue, Xin; Sun, Shan-Liang; Wang, Xiao-Long; Li, Nian-Guang; Shi, Zhi-Hao.

Bioorg Med Chem ; 100: 117631, 2024 Feb 15.

Artigo Inglês | MEDLINE | ID: mdl-38330848

10.

Characterizing the spectrum of bladder health and lower urinary tract symptoms among men: Results from the CARDIA study.

Markland, Alayne D; Hellemann, Gerhard; Shan, Liang; Brady, Sonya S; Huling, Jared D; Schreiner, Pamela J; Sidney, Stephen; Van Den Eeden, Stephen K; Lewis, Cora E.

Neurourol Urodyn ; 43(4): 840-848, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38407331

11.

Reconstruction of a three-dimensional temperature field in flames based on ES-ResNet18.

Shan, Liang; Tang, Cheng-Feng; Hong, Bo; Kong, Ming.

Appl Opt ; 63(8): 1982-1990, 2024 Mar 10.

Artigo Inglês | MEDLINE | ID: mdl-38568638

12.

Linguistic dissection of nursing handoffs: Implications for patient safety in varied-acuity hospital settings.

Galatzan, Benjamin J; Johnson, Elizabeth; Judson, Tonya; Shan, Liang.

J Clin Nurs ; 2024 Apr 25.

Artigo Inglês | MEDLINE | ID: mdl-38661339

13.

Adverse Childhood Experiences and Lower Urinary Tract Symptoms and Impact Among Women.

Brady, Sonya S; Arguedas, Andrés; Huling, Jared D; Shan, Liang; Lewis, Cora E; Fok, Cynthia S; Van Den Eeden, Stephen K; Markland, Alayne D.

J Urol ; 209(6): 1167-1175, 2023 06.

Artigo Inglês | MEDLINE | ID: mdl-36812394

14.

DMBT1 Alleviates Nasal Airway Inflammatory Response in the LPS-Induced Nasal Polyp Model.

Lu, Xiaoqing; Xu, He; Shan, Liang; Gao, Jinfeng; Tong, Jun.

Int Arch Allergy Immunol ; 184(8): 808-813, 2023.

Artigo Inglês | MEDLINE | ID: mdl-37232026

15.

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.

Zhu, Shu; Ding, Siyuan; Wang, Penghua; Wei, Zheng; Pan, Wen; Palm, Noah W; Yang, Yi; Yu, Hua; Li, Hua-Bing; Wang, Geng; Lei, Xuqiu; de Zoete, Marcel R; Zhao, Jun; Zheng, Yunjiang; Chen, Haiwei; Zhao, Yujiao; Jurado, Kellie A; Feng, Ningguo; Shan, Liang; Kluger, Yuval; Lu, Jun; Abraham, Clara; Fikrig, Erol; Greenberg, Harry B; Flavell, Richard A.

Nature ; 546(7660): 667-670, 2017 06 29.

Artigo Inglês | MEDLINE | ID: mdl-28636595

16.

Particle size distribution inversion using the Weibull-distribution adaptive-parameters cuckoo search algorithm.

Zhan, Honghui; Zha, Tingting; Hong, Bo; Shan, Liang.

Appl Opt ; 62(1): 235-245, 2023 Jan 01.

Artigo Inglês | MEDLINE | ID: mdl-36606870

17.

Analytical method for calculating internal stray radiation from an IR spectrometer based on the view factor.

Zhang, Zhi-Nan; Li, Li-Bo; Hu, Bing-Liang; Wang, Peng-Chong; Yang, Ying; Ke, Shan-Liang; Wang, Shuang; Li, Si-Yuan.

Appl Opt ; 62(3): 725-734, 2023 Jan 20.

Artigo Inglês | MEDLINE | ID: mdl-36821278

18.

Discovery of 4-(4-aminophenyl)-6-phenylisoxazolo[3,4-b]pyridine-3-amine derivatives as novel FLT3 covalent inhibitors for the intervention of acute myeloid leukemia.

Wang, Qing-Xin; Wang, Yi-Bo; Sha, Jiu-Kai; Zhou, Hai; Liu, Jia-Chuan; Wu, Jia-Zhen; Tong, Zhen-Jiang; Cai, Jiao; Chen, Zi-Jun; Zhang, Chen-Qian; Zheng, Xin-Rui; Wang, Jing-Jing; Wang, Xiao-Long; Xue, Xin; Yu, Yan-Cheng; Ding, Ning; Leng, Xue-Jiao; Dai, Wei-Chen; Sun, Shan-Liang; Chang, Liang; Li, Nian-Guang; Shi, Zhi-Hao.

Drug Dev Res ; 84(2): 296-311, 2023 04.

Artigo Inglês | MEDLINE | ID: mdl-36644989

19.

Evaluation of HIV-1 latency reversal and antibody-dependent viral clearance by quantification of singly spliced HIV-1 vpu/env mRNA.

Gao, Hongbo; Ozantürk, Ayse N; Wang, Qiankun; Harlan, Gray H; Schmitz, Aaron J; Presti, Rachel M; Deng, Kai; Shan, Liang.

J Virol ; 95(11)2021 05 10.

Artigo Inglês | MEDLINE | ID: mdl-33762408

20.

Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.

Kang, Ji-Bo; Chen, Lu; Leng, Xue-Jiao; Wang, Jing-Jing; Cheng, Yang; Wu, Shi-Han; Ma, Yi-Yuan; Yang, Li-Jin; Cao, Yu-Hao; Yang, Xiao; Tong, Zhen-Jiang; Wu, Jia-Zhen; Wang, Yi-Bo; Zhou, Hai; Liu, Jia-Chuan; Ding, Ning; Dai, Wei-Chen; Yu, Yan-Cheng; Xue, Xin; Sun, Shan-Liang; Dai, Xiao-Bin; Chang, Liang; Wang, Xiao-Long; Li, Nian-Guang; Shi, Zhi-Hao.

Bioorg Med Chem ; 70: 116937, 2022 09 15.

Artigo Inglês | MEDLINE | ID: mdl-35863236

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